If you don't have AC, how often are you running a dehumidifier? How do you control the temperature and humidity in your home?

We live in an old home in a pretty rural area. One time we kept the windows closed while we traveled for 2 weeks and came back to literally all our furniture, clothes, and rugs covered in mold.

We usually keep the windows open and fans running 24/7 for airflow but things feel permanently damp lately so we've been running dehumidifiers when it's cool enough to close up the house.

We've had termite swarms in the evenings lately so we've been closing all the windows. Also trying to get allergens/dust mites/mold under control.

I'm just confused like I feel like it's a waste to run the dehumidifier in the evenings if I'm just going to open up the house in the late morning and immediately have the indoor humidity shoot to 85 ?? But it's not like I'm going to run the dehumidifiers and extra fans 24/7 it'd be crazy expensive

We have one large dehumidifier on the main level near the kitchen / laundry. Then another small one in one bedroom. Thinking ab getting even one more little dehumidifier to put in the closet bc our clothes feel permanently musty?? It seems excessive but ???

What is everyone else without AC doing? Are there any tricks to keeping the air and fabrics clean / low moisture in this climate ?

Thanks